Abstract
Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.
Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis
Inflammation & Allergy - Drug Targets (Discontinued)
Title:Pentoxifylline Use in Dermatology
Volume: 11 Issue: 6
Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic and Ulker Gul
Affiliation:
Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis
Abstract: Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.
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Cite this article as:
Kulcu Cakmak Seray, Cakmak Atil, Gonul Muzeyyen, Kilic Arzu and Gul Ulker, Pentoxifylline Use in Dermatology, Inflammation & Allergy - Drug Targets (Discontinued) 2012; 11 (6) . https://dx.doi.org/10.2174/187152812803590028
DOI https://dx.doi.org/10.2174/187152812803590028 |
Print ISSN 1871-5281 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4055 |
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