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Current Cardiology Reviews


ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

Hybrid Stress Testing by Adenosine Infusion and Exercise Myocardial Perfusion Imaging: A Critical Appraisal

Author(s): Todd A. Dorfman and Ami E. Iskandrian

Volume 3, Issue 3, 2007

Page: [185 - 189] Pages: 5

DOI: 10.2174/1573403X10703030185

Price: $65


Approximately, 10 million stress myocardial perfusion images (MPI) are performed each year in the Unites States for the diagnosis of coronary artery disease (CAD) and risk assessment. Pharmacologic stress accounts for nearly 40% of these studies, and adenosine is the most widely used stress agent at present. The relative role of adenosine versus the newer and as of yet unapproved selective A-2 agonist is currently under intense study. The purpose of this review is to critically assess the role and utility of combined exercise and adenosine, so called hybrid stress testing (HST). The discussion will focus on adenosine, because HST of other combinations is well accepted such as dobutamine plus atropine and exercise combined with dipyridamole.

Keywords: Hybrid stress testing, adenosine, treadmill exercise testing, myocardial perfusion imaging, singe photon emission computed tomography

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