Abstract
Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.
Keywords: Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal
Current Gene Therapy
Title:Adenovirus Vectors and Subviral Particles for Protein and Peptide Delivery
Volume: 12 Issue: 5
Author(s): Matthias W. Kron and Florian Kreppel
Affiliation:
Keywords: Protein delivery, adenovirus vector, adenovirus subviral particles, peptide delivery, gene transfer vectors, vector capsids, epidermal growth factor, endosomal
Abstract: Adenovirus vectors belong to the most frequently used vector type in gene therapy approaches. In addition, adenovirus vector particles and adenovirus subviral particles offer a great potential for the direct delivery of proteins into cells. In this review we discuss this potential and the technology of adenovirus as a protein delivery platform for applications ranging from vaccination to gene therapy.
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Cite this article as:
W. Kron Matthias and Kreppel Florian, Adenovirus Vectors and Subviral Particles for Protein and Peptide Delivery, Current Gene Therapy 2012; 12 (5) . https://dx.doi.org/10.2174/156652312802762563
DOI https://dx.doi.org/10.2174/156652312802762563 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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