Abstract
This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the 11C- and 18F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.
Keywords: Dopamine, D2, D3, D4, dopamine receptor, selectivity, subtype-selectivity, positron emission tomography, PET, radioligand, PET ligand, radiopharmaceutical, F-18, C-11
Current Medicinal Chemistry
Title:Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments
Volume: 19 Issue: 23
Author(s): A. Banerjee and O. Prante
Affiliation:
Keywords: Dopamine, D2, D3, D4, dopamine receptor, selectivity, subtype-selectivity, positron emission tomography, PET, radioligand, PET ligand, radiopharmaceutical, F-18, C-11
Abstract: This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the 11C- and 18F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.
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Cite this article as:
Banerjee A. and Prante O., Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments, Current Medicinal Chemistry 2012; 19 (23) . https://dx.doi.org/10.2174/092986712802002518
DOI https://dx.doi.org/10.2174/092986712802002518 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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