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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

Author(s): A. Banerjee and O. Prante

Volume 19 , Issue 23 , 2012

Page: [3957 - 3966] Pages: 10

DOI: 10.2174/092986712802002518

Price: $65

Abstract

This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the 11C- and 18F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.

Keywords: Dopamine, D2, D3, D4, dopamine receptor, selectivity, subtype-selectivity, positron emission tomography, PET, radioligand, PET ligand, radiopharmaceutical, F-18, C-11


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