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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Dual Action-Based Approaches to Antibacterial Agents

Author(s): John B. Bremner, Joseph I. Ambrus and Siritron Samosorn

Volume 14 , Issue 13 , 2007

Page: [1459 - 1477] Pages: 19

DOI: 10.2174/092986707780831168

Price: $65


This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)

Keywords: Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs

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