Generic placeholder image

Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Supramolecular Host-Guest Asymmetric Induction In Organic Synthesis

Author(s): Maria Del Pilar C. Soriano, Mario J. Simirgiotis, Yaneris Mirabal-Gallardo and Leonardo S. Santos

Volume 9, Issue 3, 2012

Page: [279 - 309] Pages: 31

DOI: 10.2174/157017912801270603

Price: $65

Abstract

In past decades, the pharmacopoeia was dominated by racemates, but since the emergence of new technologies in the 1990s that allowed the preparation of pure enantiomers in significant quantities, the awareness and interest in the stereochemistry of drug actions have increased. In this short review, the implementation of several hosts, guests, building blocks and methods in host-guest supramolecular chemistry was outlined with an emphasis on the synthetic aspects, catalyst libraries and molecular recognition. Solid-state host-guest interactions, intra- and intermolecular host-guest photoreactions in solution and in the solid state, molecular and supramolecular self-assembly and molecular recognition between host and guests, and some specific and important reactions, such as aldol and Michael reactions, were reviewed.

Keywords: Asymmetric, catalyst libraries, chiral auxiliary, combinatorial chemistry, host-guest, photochirogenesis, self-assembly, supramolecular

Next »

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy