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Recent Patents on Food, Nutrition & Agriculture

Editor-in-Chief

ISSN (Print): 2212-7984
ISSN (Online): 1876-1429

Applications and Case Studies of the Next-Generation Sequencing Technologies in Food, Nutrition and Agriculture

Author(s): George E. Liu

Volume 1, Issue 1, 2009

Page: [75 - 79] Pages: 5

DOI: 10.2174/2212798410901010075

Abstract

The next-generation sequencing technologies are able to produce millions of short sequence reads in a highthroughput, cost-effective fashion. The emergence of these technologies has not only facilitated genome sequencing but also started to change the landscape of life sciences. Here, I survey their major applications ranging from whole-genome sequencing and resequencing, single nucleotide polymorphism (SNP) and structural variation discovery, to mRNA and noncoding RNA profiling and protein-nucleic acid interaction assay. These case studies in structural, functional and comparative genomics, metagenomics, and epigenomics are providing a more complete picture of the genome structures and functions. In the near future, we will witness broad impacts of these next-generation sequencing technologies for solving the complex biological problems in food, nutrition and agriculture. In this article, recent patents based information is also included.

Keywords: Sequencing, resequencing, structural genomics, functional genomics, comparative genomics, metagenomics, epigenomics


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