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Recent Patents on DNA & Gene Sequences

Editor-in-Chief

ISSN (Print): 1872-2156
ISSN (Online): 2212-3431

Recent Patents Involving Virus Nucleotide Sequences; Host Defense, RNA Silencing and Expression Vector Strategies

Author(s): Tauqeer Ahmad, Mounir AbouHaidar and Kathleen L. Hefferon

Volume 5 , Issue 3 , 2011

Page: [202 - 213] Pages: 12

DOI: 10.2174/187221511797636275

Price: $65

Abstract

Improved knowledge of the molecular biology of viruses, including recent gains in virus sequence data analysis, has greatly contributed to recent innovations in medical diagnostics, therapeutics, drug development and other related areas. Virus sequences have been used for the development of vaccines and antiviral agents to block the spread of viral infections, as well as to target and battle chronic diseases such as cancer. Virus sequences are now routinely employed in a wide array of RNA silencing technologies. Viruses can also be engineered into expression vectors which in turn can be used as protein production platforms as well as delivery vehicles for gene therapies. This review article outlines a number of patents that have been recently issued with respect to virus sequence data and describes some of their biotechnological applications.

Keywords: Oncolytic virus, gene silencing, virus expression vector, vaccine, antiviral agents, Virus Nucleotide, Sequences, Host Defense, RNA Silencing, Expression Vector Strategies, Viruses to Treat Diseases, Kill Cancer Cells, cytokines, hepatitis C, Prodrugs of HIV, nucleoside phosphates, neoplasms


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