Implication of Oncogenic Signaling Pathways as a Treatment Strategy for Neurodegenerative Disorders – Contemporary Approaches

Title: Implication of Oncogenic Signaling Pathways as a Treatment Strategy for Neurodegenerative Disorders – Contemporary Approaches

Volume: 10 Issue: 2

Author(s): Adrian Sieradzki, Bharat B. Yendluri, Hector H. Palacios, Kalpana Parvathaneni, V. Prakash Reddy, Mark E. Obrenovich, Kazimierz Gasiorowski, Jerzy Leszek and Gjumrakch Aliev

Affiliation:

Keywords: Alzheimer's disease, Parkinson's disease, oncogenes, cell cycle, mitochondria

Abstract: Recent evidence has associated the aberrant, proximal re-expression of various cell cycle control elements with neuronal cell vulnerability in Alzheimers and Parkinsons diseases, as a common chronic neurodegeneration. This phenomenon associated with oncogenic transduction pathways activation has attracted the interest of scientists all over the world for a few years now. The purpose of this paper is to outline areas of research related to oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.

Cite this article as:

Sieradzki Adrian, B. Yendluri Bharat, H. Palacios Hector, Parvathaneni Kalpana, Prakash Reddy V., E. Obrenovich Mark, Gasiorowski Kazimierz, Leszek Jerzy and Aliev Gjumrakch, Implication of Oncogenic Signaling Pathways as a Treatment Strategy for Neurodegenerative Disorders – Contemporary Approaches, CNS & Neurological Disorders - Drug Targets 2011; 10(2) . https://dx.doi.org/10.2174/187152711794480410