Feline Immunodeficiency Virus (FIV) as A Model for Study of Lentivirus Infections: Parallels with HIV

Title: Feline Immunodeficiency Virus (FIV) as A Model for Study of Lentivirus Infections: Parallels with HIV

Volume: 8 Issue: 1

Author(s): John H. Elder, Ying-Chuan Lin, Elizabeth Fink and Chris K. Grant

Affiliation:

Abstract: FIV is a significant pathogen in the cat and is, in addition, the smallest available natural model for the study of lentivirus infections. Although divergent at the amino acid level, the cat lentivirus has an abundance of structural and pathophysiological commonalities with HIV and thus serves well as a model for development of intervention strategies relevant to infection in both cats and man. The following review highlights both the strengths and shortcomings of the FIV/cat model, particular as regards development of antiviral drugs.

Cite this article as:

Elder H. John, Lin Ying-Chuan, Fink Elizabeth and Grant K. Chris, Feline Immunodeficiency Virus (FIV) as A Model for Study of Lentivirus Infections: Parallels with HIV, Current HIV Research 2010; 8(1) . https://dx.doi.org/10.2174/157016210790416389