Applications of Supercritical Fluid Chromatography-Tandem Mass Spectrometry in Pharmaceuticals

Title: Applications of Supercritical Fluid Chromatography-Tandem Mass Spectrometry in Pharmaceuticals

Volume: 6 Issue: 3

Author(s): Maria Espinosa Bosch, Antonin Jesus Ruiz Sanchez, Fuensanta Sanchez Rojas and Catalina Bosch Ojeda

Affiliation:

Abstract: Supercritical fluid chromatography (SFC) is a fully mature technique and can readily be coupled to mass spectrometers relatively easily. In the last years, supercritical fluid chromatography coupled with mass spectrometry (SFCMS) has had a great advance in productivity, due to increase in reliability and robustness of both SFC and MS systems, the need to push drug discovery faster, and as a potential solution to old problems unsolved and new problems yet to be encountered. This article will illustrate the role of SFC-MS analysis in drug discovery process.

Cite this article as:

Bosch Espinosa Maria, Sanchez Jesus Ruiz Antonin, Rojas Sanchez Fuensanta and Ojeda Bosch Catalina, Applications of Supercritical Fluid Chromatography-Tandem Mass Spectrometry in Pharmaceuticals, Current Drug Discovery Technologies 2009; 6 (3) . https://dx.doi.org/10.2174/157016309789054942