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CNS & Neurological Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Neurogenesis and Stroke

Author(s): David A. Greenberg

Volume 6, Issue 5, 2007

Page: [321 - 325] Pages: 5

DOI: 10.2174/187152707783220901

Price: $65

Abstract

Stroke stimulates neurogenesis in select regions of the adult brain, and the newborn neurons that result can migrate to areas of ischemic injury, where they may have the capacity to enhance brain recovery. These observations suggest that stroke-induced neurogenesis may contribute to endogenous brain repair after stroke, and that the mechanisms that underlie neurogenesis may represent potential therapeutic targets. Alternatively, transplantation of exogenously derived neural cells might also be an approach to the treatment of stroke.

Keywords: Stroke, ischemia, neurogenesis, proliferation, migration, differentiation


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