Generic placeholder image

Current Respiratory Medicine Reviews


ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

New Developments in Molecular Diagnosis of Bacteremic Pneumococcal Pneumonia

Author(s): Cordelia Kee, Ian Kay and Grant W. Waterer

Volume 7, Issue 4, 2011

Page: [246 - 249] Pages: 4

DOI: 10.2174/157339811798281269

Price: $65


The management of community-acquired pneumonia remains mainly driven by empiric antibiotic therapy because existing microbiological techniques are relatively insensitive and rarely deliver an answer within a useful time frame. Advances in the molecular detection of Streptococcus pneumoniae in whole blood have been published that suggest that a new era of diagnostics may be ready for routine clinical practice. As well as improved sensitivity over existing culture techniques and a very high specificity, the new assays quantitate the amount of bacteremia which appears to be an extremely useful prognostic marker. Here we review the recent studies and their implications in the setting of pneumococcoal pneumonia.

Keywords: Pneumococcus, PCR, quantitative, bacterial load, Molecular Diagnosis, community-acquired pneumonia, antibiotic therapy, blood, culture techniques, high specificity, alpha-hemolytic, respiratory tract, real-time PCR, DNA

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy