Anhydrous FePO4 as a Cost-Effective and Recyclable Catalyst for Tetrahydropyranylation and Tetrahydrofuranylation of Alcohols and Phenols

Title: Anhydrous FePO4 as a Cost-Effective and Recyclable Catalyst for Tetrahydropyranylation and Tetrahydrofuranylation of Alcohols and Phenols

Volume: 8 Issue: 6

Author(s): Farahnaz K. Behbahani and Mona Farahani

Affiliation:

Keywords: Alcohols, anhydrous FePO4, deprotection, phenols, protection, THF ethers, THP ethers, hydroxyl groups, benzylic alcohols, tetrahydropyranylation

Abstract: In this article, a mild and efficient protocol for the tetrahydropyranylation and tetrahydrofuranylation of various aliphatic and benzylic alcohols and phenols into their corresponding THP and THF ethers (with 3,4-dihydro- 2H-pyran, DHP and 2,3-dihydrofuran, DHF) has been developed using a catalytic amount of anhydrous FePO4 at room temperature and relatively short reaction times in good to excellent yields.

Cite this article as:

K. Behbahani Farahnaz and Farahani Mona, Anhydrous FePO4 as a Cost-Effective and Recyclable Catalyst for Tetrahydropyranylation and Tetrahydrofuranylation of Alcohols and Phenols, Letters in Organic Chemistry 2011; 8 (6) . https://dx.doi.org/10.2174/157017811796064485