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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of N1- and N8-(γ -L-Glutamyl)spermidines and (γ -L-Glutamyl) putrescine

Author(s): Kazuya Toho, Naoki Abe, Teiko Yamada, Yoshifumi Ito, Hiroyuki Konno, Shigefumi Kuwahara and Hiromasa Kiyota

Volume 8 , Issue 1 , 2011

Page: [1 - 4] Pages: 4

DOI: 10.2174/157017811794557813

Price: $65

Abstract

(γ-L-Glutamyl)putrescine and N1- and N8-(γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.

Keywords: glutamylspermidine, glutamylputrescine, Pseudomonas aeruginosa, polyamine biosynthesis, polyamine glutamyl transferase


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