Abstract
Fullerenes, the third carbon allotrope, have emerged as agents which could revolutionize the treatment of many diseases. Fullerenes possess different biological applications like neuroprotective agents, antioxidants, anti-HIV activity, enzyme inhibition, antiapoptotic activity and the list is ever increasing. Moreover, they are being utilized as drug carrier systems and also for many non-biological applications like superconductors, catalysis and so on. Their size has made them promising agents for nanotechnology. This article aims at outlining the chemistry, properties and non-biological applications of fullerenes and their evolution to biological applications, thereby traversing their evolution from simple carbon allotropes to present day nano-medicinal agents.
Keywords: Anti HIV, antioxidant, antiapoptotic, enzyme inhibition, nanomedicines, neuroprotective
Mini-Reviews in Medicinal Chemistry
Title: Fullerenes: From Carbon to Nanomedicine
Volume: 10 Issue: 8
Author(s): Pooja Chawla, Viney Chawla, Radhika Maheshwari, Shubhini A. Saraf and Shailendra K. Saraf
Affiliation:
Keywords: Anti HIV, antioxidant, antiapoptotic, enzyme inhibition, nanomedicines, neuroprotective
Abstract: Fullerenes, the third carbon allotrope, have emerged as agents which could revolutionize the treatment of many diseases. Fullerenes possess different biological applications like neuroprotective agents, antioxidants, anti-HIV activity, enzyme inhibition, antiapoptotic activity and the list is ever increasing. Moreover, they are being utilized as drug carrier systems and also for many non-biological applications like superconductors, catalysis and so on. Their size has made them promising agents for nanotechnology. This article aims at outlining the chemistry, properties and non-biological applications of fullerenes and their evolution to biological applications, thereby traversing their evolution from simple carbon allotropes to present day nano-medicinal agents.
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Cite this article as:
Chawla Pooja, Chawla Viney, Maheshwari Radhika, A. Saraf Shubhini and K. Saraf Shailendra, Fullerenes: From Carbon to Nanomedicine, Mini-Reviews in Medicinal Chemistry 2010; 10 (8) . https://dx.doi.org/10.2174/138955710791572497
DOI https://dx.doi.org/10.2174/138955710791572497 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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