Abstract
A dimeric 34-kDa antifungal protein, designated as acafusin, was purified from Acacia confusa seeds using Q-Sepharose, DEAE-cellulose, Mono S and Superdex S75. It demonstrated antifungal activity toward Rhizoctonia solani with an IC50 of 28 μM. Acafusin inhibited the activity of HIV-1 reverse transcriptase mildly with an IC50 of 80 μM.
Keywords: Acacia confusa, antifungal protein, HIV-1 reverse transcriptase inhibitory
Protein & Peptide Letters
Title: Acafusin, a Dimeric Antifungal Protein from Acacia confusa Seeds
Volume: 17 Issue: 7
Author(s): Sze Kwan Lam and Tzi Bun Ng
Affiliation:
Keywords: Acacia confusa, antifungal protein, HIV-1 reverse transcriptase inhibitory
Abstract: A dimeric 34-kDa antifungal protein, designated as acafusin, was purified from Acacia confusa seeds using Q-Sepharose, DEAE-cellulose, Mono S and Superdex S75. It demonstrated antifungal activity toward Rhizoctonia solani with an IC50 of 28 μM. Acafusin inhibited the activity of HIV-1 reverse transcriptase mildly with an IC50 of 80 μM.
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Cite this article as:
Kwan Lam Sze and Bun Ng Tzi, Acafusin, a Dimeric Antifungal Protein from Acacia confusa Seeds, Protein & Peptide Letters 2010; 17 (7) . https://dx.doi.org/10.2174/092986610791306643
DOI https://dx.doi.org/10.2174/092986610791306643 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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