Abstract
One of the main components of snake venoms are the Asp49-phospholipases A2, also known as svPLA2s. The study of these toxins is a matter of great scientific interest due to their wide variety of biological effects. In this work we present strong evidences found in literature and other aspects which strengthen the importance of quaternary assembly for understanding the activities and molecular evolution of svPLA2s.
Keywords: Phospholipase A2, oligomerization, quaternary conformation, snake venom
Protein & Peptide Letters
Title: Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms
Volume: 16 Issue: 8
Author(s): Angelo J. Magro, Carlos A.H. Fernandes, Juliana I. dos Santos and Marcos R.M. Fontes
Affiliation:
Keywords: Phospholipase A2, oligomerization, quaternary conformation, snake venom
Abstract: One of the main components of snake venoms are the Asp49-phospholipases A2, also known as svPLA2s. The study of these toxins is a matter of great scientific interest due to their wide variety of biological effects. In this work we present strong evidences found in literature and other aspects which strengthen the importance of quaternary assembly for understanding the activities and molecular evolution of svPLA2s.
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Cite this article as:
Magro J. Angelo, Fernandes A.H. Carlos, dos Santos I. Juliana and Fontes R.M. Marcos, Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms, Protein & Peptide Letters 2009; 16 (8) . https://dx.doi.org/10.2174/092986609788923301
DOI https://dx.doi.org/10.2174/092986609788923301 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
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