Abstract
Melatonin is a neurohormone that has attracted a great deal of attention, being frequently investigated in recent years. Due to its wide-spectrum of properties, melatonin has been suggested to be effective with respect to the etiology and treatment of several diseases. Its action on the immune system and antioxidant features has brought interest to this hormones role in chronic inflammatory diseases. Furthermore, the detection of a correlation between the circadian release of melatonin and the rhythmic symptoms and signs of rheumatoid patients has led scientists to address its involvement in rheumatic diseases. Studies with suitable methodologies and broad perspectives are required in order to determine the functions of this neurohormone, whose effects are dependent on its physiological and pharmacological doses.
Keywords: Melatonin, rhematoid arthritis, fibromyalgia, antioxidant, circadian rhythm
Infectious Disorders - Drug Targets
Title: The Role of Melatonin in Rheumatic Diseases
Volume: 9 Issue: 4
Author(s): B. Kalpakcioglu and K. Senel
Affiliation:
Keywords: Melatonin, rhematoid arthritis, fibromyalgia, antioxidant, circadian rhythm
Abstract: Melatonin is a neurohormone that has attracted a great deal of attention, being frequently investigated in recent years. Due to its wide-spectrum of properties, melatonin has been suggested to be effective with respect to the etiology and treatment of several diseases. Its action on the immune system and antioxidant features has brought interest to this hormones role in chronic inflammatory diseases. Furthermore, the detection of a correlation between the circadian release of melatonin and the rhythmic symptoms and signs of rheumatoid patients has led scientists to address its involvement in rheumatic diseases. Studies with suitable methodologies and broad perspectives are required in order to determine the functions of this neurohormone, whose effects are dependent on its physiological and pharmacological doses.
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Cite this article as:
Kalpakcioglu B. and Senel K., The Role of Melatonin in Rheumatic Diseases, Infectious Disorders - Drug Targets 2009; 9 (4) . https://dx.doi.org/10.2174/187152609788922546
DOI https://dx.doi.org/10.2174/187152609788922546 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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