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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Solid-Phase Synthesis of 2-Iodomethyl-2,3-dihydrobenzofurans Using Recyclable Polymer-Supported Selenium Bromide

Author(s): Shouri Sheng, Minggang Hu, Dan Wu, Mingzhong Cai and Xian Huang

Volume 6, Issue 4, 2009

Page: [345 - 348] Pages: 4

DOI: 10.2174/157017809788489837

Price: $65

Abstract

Reaction of polymer-supported selenium bromide with ortho allylated phenols and subsequent cleavage from the polymer by treatment of methyl iodide efficiently afforded 2-iodomethyl-2,3-dihydrobenzofurans in good yields and high purities. The polymeric reagent can be regenerated and reused as environmentally friendly reagent.

Keywords: Solid-phase organic synthesis, Polymer-supported selenium bromide, Recyclable, Selenium mediated intramolecular cyclization, 2-Iodomethyl-2,3-dihydrobenzofuran, Traceless cleavage


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