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Infectious Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Drug Targets in Infections with Ebola and Marburg Viruses

Author(s): Olinger G. Gene, Biggins E. Julia, Melanson R. Vanessa, Wahl-Jensen Victoria, Geisbert W. Thomas and Hensley E. Lisa

Volume 9 , Issue 2 , 2009

Page: [191 - 200] Pages: 10

DOI: 10.2174/187152609787847730

Price: $65

Abstract

The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.

Keywords: Filoviridae, Ebola virus, Marburg virus, drug targets, therapeutics, pathogenesis, pathology, immunotherapy


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