Drug Targets in Infections with Ebola and Marburg Viruses

Title: Drug Targets in Infections with Ebola and Marburg Viruses

Volume: 9 Issue: 2

Author(s): Olinger G. Gene, Biggins E. Julia, Melanson R. Vanessa, Wahl-Jensen Victoria, Geisbert W. Thomas and Hensley E. Lisa

Affiliation:

Keywords: Filoviridae, Ebola virus, Marburg virus, drug targets, therapeutics, pathogenesis, pathology, immunotherapy

Abstract: The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies, or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.

Cite this article as:

Gene G. Olinger, Julia E. Biggins, Vanessa R. Melanson, Victoria Wahl-Jensen, Thomas W. Geisbert and Lisa E. Hensley, Drug Targets in Infections with Ebola and Marburg Viruses, Infectious Disorders - Drug Targets 2009; 9 (2) . https://dx.doi.org/10.2174/187152609787847730