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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

One-pot Synthesis of 2-Substituted Imidazo[2,1-b][1,3]benzothiazoles via Coupling-Cyclization Under Pd-Cu Catalysis in Water

Author(s): Mohammad Bakherad, Ali Keivanloo and Mahdieh Hashemi

Volume 6, Issue 2, 2009

Page: [165 - 170] Pages: 6

DOI: 10.2174/157017809787582717

Price: $65

Abstract

The reaction of 2-imino-3-(2-propynyl)-1,3-benzothiazole with various aryl iodides, catalyzed by Pd-Cu, in the presence of sodium lauryl sulfate as the surfactant and potassium carbonate as the base, in water, leads to the formation of 2-substituted imidazo[2,1-b][1,3]benzothiazoles.

Keywords: Sonogashira coupling, aryl iodide, imidazo[2,1-b][1,3]benzothiazole, Pd-catalyzed, potassium carbonate, sodium lauryl sulfate


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