Abstract
Currently the only treatment for celiac disease is adherence to a strict gluten-free diet; however, compliance with this diet is complex and other alternatives are called for. Herein, we review recent developments in the design of novel therapeutic strategies to counteract the pathogenic effects of the interactions between gluten peptides and their specific biological targets.
Keywords: Celiac disease, gluten, immunity, permeability, therapy, intestinal microbiota, probiotics
Mini-Reviews in Medicinal Chemistry
Title: Novel Perspectives in Celiac Disease Therapy
Volume: 9 Issue: 3
Author(s): Yolanda Sanz
Affiliation:
Keywords: Celiac disease, gluten, immunity, permeability, therapy, intestinal microbiota, probiotics
Abstract: Currently the only treatment for celiac disease is adherence to a strict gluten-free diet; however, compliance with this diet is complex and other alternatives are called for. Herein, we review recent developments in the design of novel therapeutic strategies to counteract the pathogenic effects of the interactions between gluten peptides and their specific biological targets.
Export Options
About this article
Cite this article as:
Sanz Yolanda, Novel Perspectives in Celiac Disease Therapy, Mini-Reviews in Medicinal Chemistry 2009; 9 (3) . https://dx.doi.org/10.2174/1389557510909030359
DOI https://dx.doi.org/10.2174/1389557510909030359 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
Call for Papers in Thematic Issues
Bioprospecting of Natural Products as Sources of New Multitarget Therapies
According to the Convention on Biological Diversity, bioprospecting is the exploration of biodiversity and indigenous knowledge to develop commercially valuable products for pharmaceutical and other applications. Bioprospecting involves searching for useful organic compounds in plants, fungi, marine organisms, and microorganisms. Natural products traditionally constituted the primary source of more than ...read more
Computational Frontiers in Medicinal Chemistry
The thematic issue "Computational Frontiers in Medicinal Chemistry" provides a robust platform for delving into state-of-the-art computational methodologies and technologies that significantly propel advancements in medicinal chemistry. This edition seeks to amalgamate top-tier reviews spotlighting the latest trends and breakthroughs in the fusion of computational approaches, including artificial intelligence (AI) ...read more
Natural Products and Dietary Supplements in Alleviation of Metabolic, Cardiovascular, and Neurological Disorders
Metabolic disorders like diabetes, obesity, inflammation, oxidative stress, cancer etc, cardiovascular disorders like angina, myocardial infarction, congestive heart failure etc as well as neurological disorders like Alzheimer?s, Parkinson?s, Epilepsy, Depression, etc are the global burden. They covered the major segment of the diseases and disorders from which the human community ...read more
Natural Products in Drug Discovery
Natural products have always been one of the important ways of drug discovery due to their novel skeleton and diverse functional group characteristics. According to statistics, between 1981 and 2019, the FDA approved a total of 1,394 small molecule drugs for marketing, of which 930 marketed drugs originated from the ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
What is Known About the Antiviral Agents Active Against Bovine Viral Diarrhea Virus (BVDV)?
Current Medicinal Chemistry Obesity Therapy: How and Why?
Current Medicinal Chemistry Telomeres and their Role in Aging and Longevity
Current Vascular Pharmacology The Skeletal Muscle Environment and Its Role in Immunity and Tolerance to AAV Vector-Mediated Gene Transfer
Current Gene Therapy An Atypical Case of Fulminant Interstitial Pneumonitis Induced by Carbamazepine
Current Drug Safety Preface
Recent Advances in Inflammation & Allergy Drug Discovery In Vivo Application of beta Amyloid Oligomers: A Simple Tool to Evaluate Mechanisms of Action and New Therapeutic Approaches
Current Pharmaceutical Design The Interaction of Zinc Oxide/Green Tea Extract Complex Nanoparticles and its Effect on Monosodium Glutamate Toxicity in Liver of Rats
Current Pharmaceutical Biotechnology Zinc, Metallothioneins and Longevity: Interrelationships with Niacin and Selenium
Current Pharmaceutical Design Matrix Metallopropteinases in Heart Failure
Current Topics in Medicinal Chemistry Copeptin in Preeclampsia Development
Current Women`s Health Reviews The Effect of the Antioxidant Drug "U-74389G" on Oophoritis During Ischemia Reperfusion Injury in Rats
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry P-gp Transporter and its Role in Neurodegenerative Diseases
Current Topics in Medicinal Chemistry Synthesis and In Vitro Skin Permeation of Naproxen Conjugates with α- Alkylamino Acids
Current Drug Delivery Virus-Based RNA Silencing Agents and Virus-Derived Expression Vectors as Gene Therapy Vehicles
Recent Patents on Biotechnology Natural Products with Health Benefits from Marine Biological Resources
Current Organic Chemistry CRF Receptors as a Potential Target in the Development of Novel Pharmacotherapies for Depression
Current Pharmaceutical Design Immunoglobulin VH Domains and Beyond Design and Selection of Single-Domain Binding and Targeting Reagents
Current Pharmaceutical Biotechnology Negative Correlation between Neuregulin-4 and IL-9 Serum Levels in Patients with Coronary Artery Disease
Endocrine, Metabolic & Immune Disorders - Drug Targets Melanoma and Epigenetic Treatment: Past and Future
Anti-Cancer Agents in Medicinal Chemistry