Abstract
Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent. This drug can be used orally .When the resistance to other anti-cancer drugs such as paclitaxel menifests, noscapine might be effective. Therefore, noscapine and its analogs have great potential as novel anticancer agents.
Keywords: Noscapine, antitussive, anti-cancer, anti-mitotic, apoptosis
Recent Patents on Anti-Cancer Drug Discovery
Title: The Anti-Cancer Activity of Noscapine: A Review
Volume: 4 Issue: 1
Author(s): Massoud Mahmoudian and Parvaneh Rahimi-Moghaddam
Affiliation:
Keywords: Noscapine, antitussive, anti-cancer, anti-mitotic, apoptosis
Abstract: Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent. This drug can be used orally .When the resistance to other anti-cancer drugs such as paclitaxel menifests, noscapine might be effective. Therefore, noscapine and its analogs have great potential as novel anticancer agents.
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Cite this article as:
Mahmoudian Massoud and Rahimi-Moghaddam Parvaneh, The Anti-Cancer Activity of Noscapine: A Review, Recent Patents on Anti-Cancer Drug Discovery 2009; 4 (1) . https://dx.doi.org/10.2174/157489209787002524
DOI https://dx.doi.org/10.2174/157489209787002524 |
Print ISSN 1574-8928 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3970 |
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In recent years, traditional cancer treatments, such as surgery, chemotherapy, and radiation treatment, etc., may damage the pathological tissue and normal cells. The ideal tumor treatment should be noninvasive, eliminating the primary tumor, making the body produce systemic tumor-specific immunity, eliminating metastases, and having less /no side effects. Recent Patents ...read more
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