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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones

Author(s): Ridha Touati and Bechir Ben Hassine

Volume 5 , Issue 3 , 2008

Page: [240 - 243] Pages: 4

DOI: 10.2174/157017808783955835

Price: $65


A series of β-aminosulfones were synthesized with high enantioselectivities via a new approach, which combines asymmetric hydrogenation of β-ketosulfones and Mitsunobu amination reaction of the corresponding β- hydroxysulfones with a significant high control of the stereochemistry.

Keywords: Catalysts, ruthenium, asymmetric hydrogenation, β-hydroxysulfones, Mitsunobu amination, β-aminosulfones

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