Generic placeholder image

Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of NH-Aziridines from Vicinal Amino Alcohols Via the Wenker Reaction: Scope and Limitation

Author(s): Min Zhu, Libo Hu, Ning Chen, Da-Ming Du and Jiaxi Xu

Volume 5 , Issue 3 , 2008

Page: [212 - 217] Pages: 6

DOI: 10.2174/157017808783955844

Price: $65

Abstract

The Wenker reaction is an efficient and practical method for the synthesis of NH-aziridines from vicinal amino alcohols. However, some limitation in the application has been reported. The scope and limitation of the Wenker reaction were investigated with a series of structurally diverse and representative vicinal amino alcohols.

Keywords: Aziridine, amino alcohol, cyclization, heterocyclic compound, Wenker reaction, synthesis


Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy