Synthesis of a Benzo[b]furyl (+)-Norcamphor-Derived Hydroperoxide: Study of the Activity as an Oxidant in Asymmetric Epoxidations

Title: Synthesis of a Benzo[b]furyl (+)-Norcamphor-Derived Hydroperoxide: Study of the Activity as an Oxidant in Asymmetric Epoxidations

Volume: 5 Issue: 3

Author(s): Alessandra Lattanzi, Giovanna Botta and Arrigo Scettri

Affiliation:

Keywords: Optically pure alkyl hydroperoxides, asymmetric epoxidation, allylic alcohols, α,β-enones, (+)-norcamphor

Abstract: Starting from easily available (+)-norcamphor and according to an established approach, the 2-benzo[b]furyl hydroperoxide exo-5 was obtained in 58% overall yield. In order to ascertain the impact of the modification on the activity of this chiral oxidant, a study was carried out employing it in the asymmetric epoxidation of an allylic alcohol and α,β- enones.

Cite this article as:

Lattanzi Alessandra, Botta Giovanna and Scettri Arrigo, Synthesis of a Benzo[b]furyl (+)-Norcamphor-Derived Hydroperoxide: Study of the Activity as an Oxidant in Asymmetric Epoxidations, Letters in Organic Chemistry 2008; 5 (3) . https://dx.doi.org/10.2174/157017808783955853