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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Efficient Acetylation and Boc Protection of Carbohydrates, Phenols and Amines

Author(s): Pintu Kumar Mandal and Anup Kumar Misra

Volume 5 , Issue 3 , 2008

Page: [194 - 201] Pages: 8

DOI: 10.2174/157017808783955880

Price: $65


An efficient acetylation and tert-butoxycarbonylation (Boc) of carbohydrate derivatives, phenols and amines catalyzed by tetrabutylammonium bromide is reported. The reaction condition is applicable to substrates containing acid and base labile functional groups. In most of the cases yields obtained were excellent.

Keywords: Carbohydrates, acetylation, tert-butoxycarbonyl, protecting groups, amines, phenols

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