Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery

Title: Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery

Volume: 5 Issue: 2

Author(s): Jose M. Rodriguez-Lopez and Francisco S. Lozano

Affiliation:

Keywords: Propofol, Systemic inflammatory response, Aortic surgery, Aortic cross-clamping

Abstract: Abdominal aortic surgery is relatively common associated with considerable postoperative morbidity and mortality. The aortic cross-clamping for the implantation of a vascular prosthetic graft induces a systemic inflammatory response (SIR) because of an ischemia-reperfusion (IR) injury. In our experimental models we have reported that propofol anesthesia, compared with sevoflurane, after IR modulates SIR and this effect might result in renal protection.

Cite this article as:

Rodriguez-Lopez M. Jose and Lozano S. Francisco, Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery, Letters in Drug Design & Discovery 2008; 5(2) . https://dx.doi.org/10.2174/157018008783928490