Abstract
Upper Airway Resistance Syndrome (UARS) was initially used to describe a group of patients who were sleepy but did not meet the diagnostic criteria of obstructive sleep apnea syndrome (OSAS). Since the original description, controversy and ambiguity of this disorder have lead to limited amounts of adequate data and studies. The incidence, prevalence, natural history, and morbidity of this disorder are not well known, and the diagnosis of UARS remains a controversial issue. Advances in technology have lead to measurement of sensitive polysomnographic variables that may aid in effectively identifying this disorder, distinguishing it from OSAS. Recognition of patients with UARS is important because although these patients are symptomatic, they may not present with the same symptoms as patients with OSAS. Treatment options are available that may benefit patients with UARS. This article reviews the pathophysiology, diagnosis, clinical picture and management of UARS.
Keywords: obstructive sleep apnea syndrome, airway pressure, EEG pattern, continuous positive airway pressure, NREM sleep
Current Respiratory Medicine Reviews
Title: Upper Airway Resistance Syndrome
Volume: 4 Issue: 1
Author(s): Christian Guilleminault and Kannan Ramar
Affiliation:
Keywords: obstructive sleep apnea syndrome, airway pressure, EEG pattern, continuous positive airway pressure, NREM sleep
Abstract: Upper Airway Resistance Syndrome (UARS) was initially used to describe a group of patients who were sleepy but did not meet the diagnostic criteria of obstructive sleep apnea syndrome (OSAS). Since the original description, controversy and ambiguity of this disorder have lead to limited amounts of adequate data and studies. The incidence, prevalence, natural history, and morbidity of this disorder are not well known, and the diagnosis of UARS remains a controversial issue. Advances in technology have lead to measurement of sensitive polysomnographic variables that may aid in effectively identifying this disorder, distinguishing it from OSAS. Recognition of patients with UARS is important because although these patients are symptomatic, they may not present with the same symptoms as patients with OSAS. Treatment options are available that may benefit patients with UARS. This article reviews the pathophysiology, diagnosis, clinical picture and management of UARS.
Export Options
About this article
Cite this article as:
Guilleminault Christian and Ramar Kannan, Upper Airway Resistance Syndrome, Current Respiratory Medicine Reviews 2008; 4 (1) . https://dx.doi.org/10.2174/157339808783497882
DOI https://dx.doi.org/10.2174/157339808783497882 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Chilling-Like Attacks Terminated by Slow Pathway Ablation
Current Cardiology Reviews Treatment of Severe Cases of Pandemic (H1N1) 2009 Influenza: Review of Antivirals and Adjuvant Therapy
Recent Patents on Anti-Infective Drug Discovery Treatment of Pulmonary Thromboembolism in Patients with Systemic Blood Pressure Stability and Right Ventricular Dysfunction
Current Respiratory Medicine Reviews Clonidine in Perioperative Medicine and Intensive Care Unit: More Than An Anti-Hypertensive Drug
Current Drug Targets Developing Specific Therapeutic Strategies for Transfusion-Related Acute Lung Injury. An Overview of Potentially Useful Animal Models
Cardiovascular & Hematological Agents in Medicinal Chemistry Current Treatment of Autoimmune Blistering Diseases
Current Drug Discovery Technologies The Management of the Infected Diabetic Foot
Current Diabetes Reviews TRPV4 Agonists and Antagonists
Current Topics in Medicinal Chemistry Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review
Recent Patents on Anti-Cancer Drug Discovery Non-IgE Mediated Food Allergy – Update of Recent Progress in Mucosal Immunity
Inflammation & Allergy - Drug Targets (Discontinued) Substance P Regulation in Epilepsy
Current Neuropharmacology The Complexes of Drugs with Carbohydrate-Containing Plant Metabolites as Pharmacologically Promising Agents
Mini-Reviews in Medicinal Chemistry Biologicals Dramatic Advances in the Treatment of Psoriasis
Current Pharmaceutical Design Activities of Venom Proteins and Peptides with Possible Therapeutic Applications from Bees and WASPS
Protein & Peptide Letters The Neurokinins: Peptidomimetic Ligand Design and Therapeutic Applications
Current Medicinal Chemistry Applications and Modifications of 1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid (Tic) in Peptides and Peptidomimetics Design and Discovery
Current Protein & Peptide Science Autoimmune Neuromuscular Disorders
Current Neuropharmacology Immunotoxicity and Immunogenicity of Biopharmaceuticals: Design Concepts and Safety Assessment
Current Drug Safety Safety Considerations of the Use of Second Generation Antipsychotics in the Treatment of Major Depression: Extrapyramidal and Metabolic Side Effects
Current Drug Safety Prevention of Atherosclerosis by Interference with the Vascular Nitric Oxide System
Current Pharmaceutical Design