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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Determination of Bioactive Constituents in Traditional Chinese Medicines by CE with Electrochemical Detection

Author(s): Gang Chen, Yizhun Zhu, Yufeng Wang, Xuejiao Xu and Tao Lu

Volume 13 , Issue 21 , 2006

Page: [2467 - 2485] Pages: 19

DOI: 10.2174/092986706778201657

Price: $65


This paper reviews the recent advances and the key strategies in capillary electrophoresis (CE) with electrochemical detection (ECD) for separating and detecting a variety of bioactive constituents in traditional Chinese medicines (TCMs). The subjects covered include the separation modes for the CE analysis of the constituents in TCMs, the CE-ECD system, the sample preparations of TCMs, the ECD of TCMs, the applications of CE-ECD in the determination of various bioactive constituents in Chinese medicinal materials and their preparations, the identification and differentiation of TCMs by CE-ECD, and future prospects. It is expected that CE-ECD will become a powerful tool in the herbal medicinal fields and will lead to the creation of truly routine devices for TCM analysis.

Keywords: Traditional Chinese medicine, pharmaceutical analysis, capillary electrophoresis, electrochemical detection, amperometry, electrode, bioactive constituent, differentiation

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