Abstract
Background. Multiple factors have been previously described which could influence adherence to HAART. Our objective is to determine the fundamental factors which influence adherence to highly active antiretroviral therapy in our population. Methods. A cross-sectional study was made selecting 143 outpatients attending our hospital HIV unit. 22 factors were recorded which could influence adherence to treatment (covering individual factors, the illness itself, the therapeutic regimen and the medical team). Adherence was estimated by the combination of two methods (self-report and pharmacy data); statistical analysis was performed using univariate and multivariate methods. Results. 96 patients (67.13%) had good adherence and 47 (32.87%) did not. Only 3 of the 22 factors studied were significant and independent factors related with adherence: employment, housing situation and degree of treatment acceptance. Conclusions. we have found some differences regarding HAART adherence in our population compared with previous studies. Psychosocial and behavioral factors were the principal ones. We must try to detect patients at high risk of nonadherence in order to take therapeutic decisions properly, try to reinforce adherence and modify the factors associated with poor adherence.
Keywords: Highly active antiretroviral therapy, patient compliance, HIV
Current HIV Research
Title: Factors Influencing Adherence to Highly Active Antiretroviral Therapy in Spain
Volume: 4 Issue: 2
Author(s): Leticia Moralejo, Sandra Ines, Miguel Marcos, Aurelio Fuertes and Guillermo Luna
Affiliation:
Keywords: Highly active antiretroviral therapy, patient compliance, HIV
Abstract: Background. Multiple factors have been previously described which could influence adherence to HAART. Our objective is to determine the fundamental factors which influence adherence to highly active antiretroviral therapy in our population. Methods. A cross-sectional study was made selecting 143 outpatients attending our hospital HIV unit. 22 factors were recorded which could influence adherence to treatment (covering individual factors, the illness itself, the therapeutic regimen and the medical team). Adherence was estimated by the combination of two methods (self-report and pharmacy data); statistical analysis was performed using univariate and multivariate methods. Results. 96 patients (67.13%) had good adherence and 47 (32.87%) did not. Only 3 of the 22 factors studied were significant and independent factors related with adherence: employment, housing situation and degree of treatment acceptance. Conclusions. we have found some differences regarding HAART adherence in our population compared with previous studies. Psychosocial and behavioral factors were the principal ones. We must try to detect patients at high risk of nonadherence in order to take therapeutic decisions properly, try to reinforce adherence and modify the factors associated with poor adherence.
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Moralejo Leticia, Ines Sandra, Marcos Miguel, Fuertes Aurelio and Luna Guillermo, Factors Influencing Adherence to Highly Active Antiretroviral Therapy in Spain, Current HIV Research 2006; 4 (2) . https://dx.doi.org/10.2174/157016206776055075
DOI https://dx.doi.org/10.2174/157016206776055075 |
Print ISSN 1570-162X |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4251 |
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Management of HIV: Management of HIV: old challenges and new needs
The aim of this thematic issue is to provide the most recent updates regarding the effective management of HIV infection. Antiretroviral therapy (ART) has significantly decreased HIV-related mortality, leading to an enhancement in the quality of life and life expectancy for people living with HIV (PLWH). Despite the numerous advancements ...read more
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