Abstract
Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.
Keywords: short chain fatty acids, butyrate, inflammation, cancer, colon and fiber
Mini-Reviews in Medicinal Chemistry
Title: Cellular and Physiological Effects of Short-Chain Fatty Acids
Volume: 4 Issue: 8
Author(s): Steven J. Miller
Affiliation:
Keywords: short chain fatty acids, butyrate, inflammation, cancer, colon and fiber
Abstract: Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.
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Cite this article as:
Miller J. Steven, Cellular and Physiological Effects of Short-Chain Fatty Acids, Mini-Reviews in Medicinal Chemistry 2004; 4 (8) . https://dx.doi.org/10.2174/1389557043403288
DOI https://dx.doi.org/10.2174/1389557043403288 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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