Abstract
A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.
Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation
Letters in Organic Chemistry
Title: A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones
Volume: 2 Issue: 7
Author(s): V. J. Sattigeri, A. S.S.V. Srinivas, A. Soni, J. M. Khanna and A. Mehta
Affiliation:
Keywords: chiral, substituted -oxazolidinones, asymmetric dihydroxylation, intramolecular cyclisation
Abstract: A novel and efficient synthesis of 4-substituted 2-oxazolidinones is described; the synthesis utilizes Sharpless asymmetric dihydroxylation (AD) of appropriately substituted O-allylcarbamates and intramolecular cyclisation as key steps.
Export Options
About this article
Cite this article as:
Sattigeri J. V., Srinivas S.S.V. A., Soni A., Khanna M. J. and Mehta A., A Simple Asymmetric Synthesis of 4-Substituted-2-Oxazolidinones, Letters in Organic Chemistry 2005; 2 (7) . https://dx.doi.org/10.2174/157017805774296876
DOI https://dx.doi.org/10.2174/157017805774296876 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy
Current Medicinal Chemistry Ligand-Receptor Communication and Drug Design
Current Protein & Peptide Science Exploration of N-arylpiperazine Binding Sites of D2 Dopaminergic Receptor
Mini-Reviews in Medicinal Chemistry Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review
Current Drug Targets Current Progresses of Novel Natural Products and Their Derivatives/ Analogs as Anti-Alzheimer Candidates: an Update
Mini-Reviews in Medicinal Chemistry Nitrofurantoin Pulmonary Toxicity: Neglected Threat
Current Drug Safety Metabotropic GABAB Receptors New Challenges in Drug Design
Current Medicinal Chemistry - Central Nervous System Agents Would the Development of a Multitarget Inhibitor of 3CL<sup>pro</sup> and TMPRSS2 be Promising in the Fight Against SARS-CoV-2?
Medicinal Chemistry Typical and Atypical Imaging Findings of Abdominal Teratomas
Current Medical Imaging The Potential of 11C-acetate PET for Monitoring the Fatty Acid Synthesis Pathway in Tumors
Current Pharmaceutical Biotechnology Treatment of Catatonia with Asenapine in a Patient with Schizotypal Personality Disorder, Psychotic Depression and Septic Shock from SARSCoV- 2 - A Case Report
CNS & Neurological Disorders - Drug Targets Recent Advances of Natural and Synthetic β-Carbolines as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Synthesis of Imidazo[1,2-b]pyridazine Comprised Piperazine, Morpholine Derivatives as Potent Antimycobacterial Agents with In Vivo Locomotor Activity
Anti-Infective Agents Histone Deacetylase Inhibitors: Potent Anti-Leukemic Agents
Current Medicinal Chemistry SAR, Cardiac Myocytes Protection Activity and 3D-QSAR Studies of Salubrinal and its Potent Derivatives
Current Medicinal Chemistry Synthesis and Cytotoxic Evaluation of Disubstituted N-Acylhydrazones Pyrazinecarbohydrazide Derivatives
Letters in Drug Design & Discovery Recent Advances in Targeting Viral Proteases for the Discovery of Novel Antivirals
Current Topics in Medicinal Chemistry G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application
Current Pharmaceutical Design Acknowledgement to Reviewers
Current Traditional Medicine Perspective of Molecular Hydrogen in the Treatment of Sepsis
Current Pharmaceutical Design