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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Functionalized, Differently Fluorinated Building-Blocks Via Michael Addition of Enamines to γ-Fluoro-α-Nitroalkenes

Author(s): M. Molteni and ">M. Zanda

Volume 2, Issue 6, 2005

Page: [566 - 568] Pages: 3

DOI: 10.2174/1570178054640769

Price: $65


The Michael addition of ketone-derived enamines to γ-fluoro-α-nitroalkenes provides in moderate to good isolated yields the corresponding β-fluoroalkyl γ-nitroketones, which can be reduced to β-fluoroalkyl γ- nitroalcohols.

Keywords: nitroalkenes, fluorinated building blocks, michael addition, diels-alder, dipolar reactions, (nitroaldol) reaction, tbaf, mukaiyama-like conditions

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