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Protein & Peptide Letters


ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Recent Developments in the Understanding of Nuclear Protein Import

Author(s): S.M. Liu and W.M. Liu

Volume 14, Issue 7, 2007

Page: [723 - 733] Pages: 11

DOI: 10.2174/092986607781483895

Price: $65


The process of nucleocytoplasmic exchange of various macromolecules and metabolites between the nuclear and cytoplasmic compartment is crucial for cell function and survival. It is also closely involved with several pathogeneses including cancer and viral infections. Here, we will discuss the current understanding of the classical nuclear import pathway and the factors that are essential for this process.

Keywords: Nuclear transport, ran switch, importin, influenza

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