Molecular Interactions of the Mitochondrial Tim12 Translocase Subunit

Title: Molecular Interactions of the Mitochondrial Tim12 Translocase Subunit

Volume: 14 Issue: 6

Author(s): Catherine Baud, Carine de Marcos-Lousa and Kostas Tokatlidis

Affiliation:

Keywords: Mitochondria, small Tims, chaperones, protein assembly

Abstract: The small Tims are chaperones that facilitate insertion of hydrophobic precursors into the inner mitochondrial membrane. We purified Tim12 and found it forms dimers that bind to Tim9. In this interaction, Tim12 undergoes structural changes that may be important for transport of its substrates in the mitochondrial carrier import pathway.

Cite this article as:

Catherine Baud , Carine de Marcos-Lousa and Kostas Tokatlidis , Molecular Interactions of the Mitochondrial Tim12 Translocase Subunit, Protein & Peptide Letters 2007; 14 (6) . https://dx.doi.org/10.2174/092986607780990019