Neuronal Self-Repair Following Cerebral Ischemic Insults

Title: Neuronal Self-Repair Following Cerebral Ischemic Insults

Volume: 7 Issue: 2

Author(s): Xinjian Zhu, Youming Lu and Dongya Zhu

Affiliation:

Keywords: Neurogenesis, cerebral ischemia, hippocampus, neuronal self-repair

Abstract: Neurogenesis continues throughout adulthood in the central nervous system in mammals. Cerebral ischemia induces neurogenesis in the subventricular zone and dentate gyrus. New neurons migrate to the granule cell layer of dentate gyrus or to the damaged CA1 region and striatum, where they differentiate into mature neurons and re-establish connections. Ischemic insults also promote axonal sprouting in ischemic penumbra. Neurogenesis and axonal sprouting may contribute to functional recovery after cerebral ischemia.

Cite this article as:

Zhu Xinjian, Lu Youming and Zhu Dongya, Neuronal Self-Repair Following Cerebral Ischemic Insults, Central Nervous System Agents in Medicinal Chemistry 2007; 7(2) . https://dx.doi.org/10.2174/187152407780831693