BXT-51072 and the Prevention of Myocardial Ischemia-Reperfusion Injury

Title: BXT-51072 and the Prevention of Myocardial Ischemia-Reperfusion Injury

Volume: 4 Issue: 2

Author(s): Roy Asaf, Shany Blum, Rachel Miller-Lotan and Andrew P. Levy

Affiliation:

Keywords: Diabetes, Myocardial ischemia-reperfusion, Oxidative stress, BXT-51072

Abstract: Oxidative stress is responsible for myocardial injury occurring after ischemia and reperfusion (IR) and has been shown to be modulated by the Haptoglobin (Hp) genotype. In this manuscript we demonstrate that the antioxidant BXT -51072, a glutathione peroxidase synthetic mimic, provides protection against IR injury in a Hp genotype dependent fashion.

Cite this article as:

Asaf Roy, Blum Shany, Miller-Lotan Rachel and Levy P. Andrew, BXT-51072 and the Prevention of Myocardial Ischemia-Reperfusion Injury, Letters in Drug Design & Discovery 2007; 4 (2) . https://dx.doi.org/10.2174/157018007779422479