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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Efficient Microwave and Phosphane-Free Synthesis of Trisubstituted Olefins via Heck Coupling

Author(s): Guya Loddo, Ornella Azzolina, Andrea Magnani, Mariangela Urbano and Simona Collina

Volume 3, Issue 1, 2006

Page: [16 - 20] Pages: 5

DOI: 10.2174/157017806774964549

Price: $65

Abstract

We describe an easy and convenient procedure for palladium-catalyzed Heck arylation of disubstituted olefins via microwave irradiation. This method of synthesis produces trisubstituted olefins under phosphane-free conditions and in very short times.

Keywords: microwave irradiation, chemical library, phosphane-free procedure, trisubstituted olefins, Heck reaction


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