Current Approaches to Prevention of Contrast Induced Acute Kidney Injury

Jimena      Blandon; Debabrata      Mukherjee

Abstract

Contrast-induced acute kidney injury is one of the leading causes of hospital-acquired acute kidney injury. Thus far, no strategies have been clearly shown to be effective in preventing contrast-induced acute kidney injury beyond thorough patient selection, meticulous hydration of the patient, and minimizing the amount of contrast used. Additional studies are needed to define the optimal means of hydration, role of commonly advocated prophylaxis strategies such as N-acetylcysteine and develop newer more novel effective therapies to prevent or minimize the risk of kidney injury.

Keywords: Contrast agents, contrast-induced acute kidney injury, creatinine, creatinine clearance, hydration, iodinated contrast, kidney injury, N-acetylcysteine, nephropathy, osmolarity