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Current Genomics

Editor-in-Chief

ISSN (Print): 1389-2029
ISSN (Online): 1875-5488

Employing Genetic Markers to Improve Diagnosis of Thyroid Tumor Fine Needle Biopsy

Author(s): Janete M. Cerutti

Volume 12 , Issue 8 , 2011

Page: [589 - 596] Pages: 8

DOI: 10.2174/138920211798120781

Price: $65

Abstract

Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred to surgery for a more accurate diagnosis. An improved test would help physicians rapidly focus treatment on true malignancies and avoid some unnecessary treatment of benign tumors. This review will discuss current molecular markers that may improve thyroid nodule diagnosis.

Keywords: Follicular thyroid carcinoma, follicular thyroid adenoma, indeterminate nodule, FNA, molecular markers, ITM1, C1orf24, Biopsy, Genetic Markers, POINT MUTATIONS


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