Abstract
Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology and medicine. Since a major focus in the latter has been on drug development and formulation, in this paper we highlight some representative studies related to such a focus, including the use of fullerenes for drug-like functions and for their improving the formulation of established drugs. Also discussed are some other potential medically relevant applications of fullerenes, such as their serving as potent agents in photodynamic therapy and magnetic imaging.
Keywords: Fullerenes, radical scavengers, drug carriers, photodynamic therapy, endofullerenes, MRI contrast agents, carbon allotropes, technological applications, amino acid, carboxylic acid, amphiphilic polymers
Current Medicinal Chemistry
Title: Fullerenes for Applications in Biology and Medicine
Volume: 18 Issue: 14
Author(s): P. Anilkumar, F. Lu, L. Cao, P. G. Luo, J.-H. Liu, S. Sahu, K. N. Tackett II, Y. Wang and Y.-P. Sun
Affiliation:
Keywords: Fullerenes, radical scavengers, drug carriers, photodynamic therapy, endofullerenes, MRI contrast agents, carbon allotropes, technological applications, amino acid, carboxylic acid, amphiphilic polymers
Abstract: Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology and medicine. Since a major focus in the latter has been on drug development and formulation, in this paper we highlight some representative studies related to such a focus, including the use of fullerenes for drug-like functions and for their improving the formulation of established drugs. Also discussed are some other potential medically relevant applications of fullerenes, such as their serving as potent agents in photodynamic therapy and magnetic imaging.
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Cite this article as:
Anilkumar P., Lu F., Cao L., G. Luo P., Liu J.-H., Sahu S., N. Tackett II K., Wang Y. and Sun Y.-P., Fullerenes for Applications in Biology and Medicine, Current Medicinal Chemistry 2011; 18 (14) . https://dx.doi.org/10.2174/092986711795656225
DOI https://dx.doi.org/10.2174/092986711795656225 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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