Abstract
Targeting imaging and enhanced radiotherapy are very important issues for decrease in diagnosis and therapy. Functionalized gold nanostructures show low toxicity and excellent optical properties, and thus, they can be used as the contrast agent in cancer cell imaging. Furthermore, gold nanostructures can enhance radiotherapy due to strong photoelectric absorption and second electron caused by gamma or X-ray irradiation. This critical review provides a recent progress in fabrication, optical properties (especially, fluorescence of nanoclusters), surface modification, targeting imaging, and enhanced radiotherapy of gold nanostructures. It will interest the radiation medicine, chemistry, spectroscopy, biochemistry, biophysics, and nanoscience communities.
Keywords: Gold nanoparticles, nanoclusters, cancer cell imaging, radiotherapy, Nanostructure, Fabrication,, Surface Modification, Targeting Imaging,, Enhanced Radiotherapy, photoelectric absorption, surface plasmon resonance, novel photolumi-nescence, Gold colloids, microwave irradiation, chemical reduction, auric acid, nanorods, nanocages, Turkevich method, sodium borohydride, Seed-mediated growth method, hydroxylamine hydrochlo-ride, hexadecyltrimethylammonium bromide, monodispersity nanorods, nanocrystals, polyvinylpyrrolidone (PVP), polyacrylamide gel electrophoresis (PAGE), near infrared (NIR) region, PEG- Au Nanoparticle Bioconjugation, Antibody-Au Nanoparticle Bioconjugation, Thiol protection, etching method, Toxicity of Nanostructures, brachytherapy, radiosensitization
Current Nanoscience
Title: Gold Nanostructure: Fabrication, Surface Modification, Targeting Imaging, and Enhanced Radiotherapy
Volume: 7 Issue: 1
Author(s): Di Wu, Xiao-Dong Zhang, Pei-Xun Liu, Liang-An Zhang, Fei-Yue Fan and Mei-Li Guo
Affiliation:
Keywords: Gold nanoparticles, nanoclusters, cancer cell imaging, radiotherapy, Nanostructure, Fabrication,, Surface Modification, Targeting Imaging,, Enhanced Radiotherapy, photoelectric absorption, surface plasmon resonance, novel photolumi-nescence, Gold colloids, microwave irradiation, chemical reduction, auric acid, nanorods, nanocages, Turkevich method, sodium borohydride, Seed-mediated growth method, hydroxylamine hydrochlo-ride, hexadecyltrimethylammonium bromide, monodispersity nanorods, nanocrystals, polyvinylpyrrolidone (PVP), polyacrylamide gel electrophoresis (PAGE), near infrared (NIR) region, PEG- Au Nanoparticle Bioconjugation, Antibody-Au Nanoparticle Bioconjugation, Thiol protection, etching method, Toxicity of Nanostructures, brachytherapy, radiosensitization
Abstract: Targeting imaging and enhanced radiotherapy are very important issues for decrease in diagnosis and therapy. Functionalized gold nanostructures show low toxicity and excellent optical properties, and thus, they can be used as the contrast agent in cancer cell imaging. Furthermore, gold nanostructures can enhance radiotherapy due to strong photoelectric absorption and second electron caused by gamma or X-ray irradiation. This critical review provides a recent progress in fabrication, optical properties (especially, fluorescence of nanoclusters), surface modification, targeting imaging, and enhanced radiotherapy of gold nanostructures. It will interest the radiation medicine, chemistry, spectroscopy, biochemistry, biophysics, and nanoscience communities.
Export Options
About this article
Cite this article as:
Wu Di, Zhang Xiao-Dong, Liu Pei-Xun, Zhang Liang-An, Fan Fei-Yue and Guo Mei-Li, Gold Nanostructure: Fabrication, Surface Modification, Targeting Imaging, and Enhanced Radiotherapy, Current Nanoscience 2011; 7 (1) . https://dx.doi.org/10.2174/157341311794480246
DOI https://dx.doi.org/10.2174/157341311794480246 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
Call for Papers in Thematic Issues
Role of nanomaterials in fabrication of coatings, Machining and Joining
The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
Advanced Inorganic Nanocomposites and Their Emerging Applications
This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
Applicability of Nanotechnology for Performance Enhancement of Clean Energy Technologies
Population growth, industrialization, and improvement in living quality would lead to further increase in energy demand in near future. Regarding the disadvantages of fossil fuels such as fluctuations in their price, high emissions of greenhouse gases and restriction of their sources, it is crucial to use and exploit alternative energy ...read more
Graphene and 2D Materials for Energy Storage and Conversion
This thematic issue will discuss the recent advances in graphene-based nanomaterials for different energy technologies. Graphene possesses a high surface area, and stable structure and exhibits many interesting electronic, optical, and mechanical properties due to its 2D crystal structure. Graphene is of both fundamental interest and suitable for a wide ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Advances in Small Molecule Inhibitors of VEGFR and EGFR Signaling Pathways
Current Topics in Medicinal Chemistry The CCL2/CCR2 Axis in the Pathogenesis of HIV-1 Infection: A New Cellular Target for Therapy?
Current Drug Targets Establishment of Conditionally Immortalized Cell Lines with Specific Functions and its Application to Differential Gene Expression Analysis by DNA Microarray Technology
Current Pharmaceutical Analysis Ellagic Acid: Cytodifferentiating and Antiproliferative Effects In Human Prostatic Cancer Cell Lines
Current Pharmaceutical Design Should the Incorporation of Structural Alerts be Restricted in Drug Design? An Analysis of Structure-Toxicity Trends with Aniline-Based Drugs
Current Medicinal Chemistry Pharmacoperones as a New Therapeutic Approach: In Vitro Identification and In vivo Validation of Bioactive Molecules
Current Drug Targets Angiogenic and Antiangiogenic Factors in Proliferative Diabetic Retinopathy
Current Diabetes Reviews Regulation of Bcl-2 Family Proteins by Posttranslational Modifications
Current Molecular Medicine In vivo Monitoring of Oxygen Levels in Human Brain Tumor Between Fractionated Radiotherapy Using Oxygen-enhanced MR Imaging
Current Medical Imaging Use of Grape Polyphenols for Promoting Human Health: A Review of Patents
Recent Patents on Food, Nutrition & Agriculture Resveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions
Current Medicinal Chemistry RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer
Current Cancer Drug Targets Aptamer-Mediated Polymeric Vehicles for Enhanced Cell-Targeted Drug Delivery
Current Drug Targets Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors
Current Topics in Medicinal Chemistry Mitochondrial Dysfunction and Targeted Drugs: A Focus on Diabetes
Current Pharmaceutical Design Bisphosphonates as Treatment of Bone Metastases
Current Pharmaceutical Design Cancer Nanotechnology: Emerging Role of Gold Nanoconjugates
Anti-Cancer Agents in Medicinal Chemistry Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform
Current Pharmaceutical Design 30 Years Lost in Anesthesia Theory
Cardiovascular & Hematological Agents in Medicinal Chemistry Sesterterpenoids with Anticancer Activity
Current Medicinal Chemistry