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Letters in Drug Design & Discovery


ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Endothelial Function and Cardiovascular Disease: The Role of Folic Acid

Author(s): Arduino A. Mangoni

Volume 3 , Issue 2 , 2006

Page: [112 - 117] Pages: 6

DOI: 10.2174/157018006775789784

Price: $65


There is increasing evidence that endothelial dysfunction is an independent predictor of outcome in cardiovascular disease. Therefore, the identification of therapeutic strategies enhancing endothelial function might provide salutary effects on the cardiovascular system. This review examines the role of the B-vitamin folic acid in modulating endothelial function.

Keywords: Folic acid, homocysteine, endothelium, atherosclerosis, nitric oxide

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