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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Recent Advances of Sensitive Electroanalytical Tools and Probes in the Study of DNA Structure

Author(s): S. Girousi, C. Serpi, S. Karastogianni and A. Ioannou

Volume 14 , Issue 19 , 2010

Page: [2300 - 2309] Pages: 10

DOI: 10.2174/138527210793351526

Price: $65


The research and development of electrochemical biosensors applied to life sciences during the past years were reviewed in the present article. In the first part of the article, a brief introduction on nanomaterial based electrochemical DNA biosensors is given. In the second part DNA biosensors and transition metal complexes with biological interest are described. Finally, the development trends of electrochemical biosensors in genetic and epigenetic testing are being discussed.

Keywords: Electrochemical biosensors, electroanalysis, nanomaterials, DNA interactions, methylated DNA, Carbon nanotubes, CNTs, singlewalled, SWNT, MWNT, carbon nanotube paste electrodes, CNTPE, carbon paste electrode, CPE, screen printed electrodes, SPCEs, Cyclic voltammetry, fluorescence spectroscopy, Differential pulse volt-ammetry, DVP, DCDE, electron transfer, ET, atomic force microscopy, AFM, highly oriented pyrolytic graphite, HOPG, electron cyclotron resonance, ECR, ethidium bro-mide, proflavine

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