Generic placeholder image

Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Application of MicroPET in Basic Epilepsy Research

Author(s): Feng Gao, Yi Guo, Shuang Wang, Mei Tian and Hong Zhang

Volume 6, Issue 1, 2010

Page: [17 - 22] Pages: 6

DOI: 10.2174/157340510790694207

Price: $65

Abstract

The precise neurobiological processes underlying epilepsy and epileptogenesis remain unknown. Animal models have been widely used to investigate the neurobiology, consequences and treatment of epileptic seizures and epilepsy. Small animal Positron Emission Tomography (microPET) can permit assessment of brain metabolic activity in the living animal, which cannot be accomplished by the traditional neuroscience techniques (e.g., histology, immunohistochemistry and autoradiography). It allows investigation of the neurobiological changes during epileptogenesis in the animal models and the variability caused by inter-animal differences can be removed since the same animal is used repeatedly. Moreover, microPET can also be used to investigate the biological effects of novel treatment strategies.

Keywords: Epilepsy, epileptogenesis, microPET


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy