Polyunsaturated Fatty Acids and Cardiovascular Disease

Title: Polyunsaturated Fatty Acids and Cardiovascular Disease

Volume: 15 Issue: 36

Author(s): Ivan Calzolari, Stefano Fumagalli, Niccolo Marchionni and Mauro Di Bari

Affiliation:

• Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics, University of Florence, via delle Oblate, 4, 50141 Florence, Italy.,Italy

Keywords: Polyunsaturated fatty acids, cardiovascular disease, sudden death, coronary heart disease, heart failure

Abstract: Several observational and experimental studies show the beneficial effects of ω-3 poly-unsaturated fatty acids (PUFA) in cardiovascular disease. The results from such studies justify supplementation of ω-3 PUFA in primary and secondary prevention of several clinical conditions, including coronary heart disease, sudden cardiac death and heart failure. Supplementation of ω-3 PUFA is also indicated as monotherapy in the treatment of hypertriglyceridemia. Analysis of their biological actions suggests a variety of anti-arrhythmic, anti-thrombotic, anti-atherosclerotic and antiinflammatory mechanisms underlying their clinical benefits.

Cite this article as:

Calzolari Ivan, Fumagalli Stefano, Marchionni Niccolo and Di Bari Mauro, Polyunsaturated Fatty Acids and Cardiovascular Disease, Current Pharmaceutical Design 2009; 15(36) . https://dx.doi.org/10.2174/138161209789909755