Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

Title: Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

Volume: 16 Issue: 36

Author(s): F. Fulop, I. Szatmari, E. Vamos, D. Zadori, J. Toldi and L. Vecsei

Affiliation:

• Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary.,Hungary

Keywords: Kynurenic acid, kynurenic acid derivatives, neurological disorders, schizophrenia, retinal damage, diabetes mellitus, hypertension

Abstract: The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.

Cite this article as:

Fulop F., Szatmari I., Vamos E., Zadori D., Toldi J. and Vecsei L., Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives, Current Medicinal Chemistry 2009; 16(36) . https://dx.doi.org/10.2174/092986709789909602