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Current Bioactive Compounds


ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Manganese Pyrazolylborate Complexes as Model for Mn-Containing Metalloproteins

Author(s): Pooja Tyagi and Udai P. Singh

Volume 5, Issue 4, 2009

Page: [296 - 320] Pages: 25

DOI: 10.2174/157340709789816429

Price: $65


This review presents an overview of the active site structure for manganese redox proteins and their model compounds. This includes manganese (II/III) complexes with pyrazoles, pyrazolylborates and biological activity of some complexes. The active site structure of native protein, synthesis, crystal structure and catalytic activity of these complexes are reviewed. The plan of the review is: 1. Introduction 2. Synthetic and structural aspect 3. Reactivity aspect 4. Conclusion

Keywords: Manganese, pyrazole, pyrazolylborate, superoxide dismutase, catalase, model complexes, ribonucleotide reductase, biological activity

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